I am a Senior Scientist at Vesalius Therapeutics. My interests are to develop and apply computational approaches to identify and characterize the biological processes driving human development and disease, and translate insights into new therapeutics.
I was previously a postdoctoral scholar at the University of Chicago working with Matthew Stephens and Yoav Gilad. I completed my Ph.D. at Massachusetts Institute of Technology in the Computational Biology group at the Computer Science and Artificial Intelligence Lab, advised by Manolis Kellis.
Separating measurement and expression models clarifies confusion in single-cell RNA sequencing analysis. Nature Genetics, 2021
A simple new approach to variable selection in regression, with application to genetic fine-mapping.Journal of the Royal Statistical Society: Series B (Statistical Methodology), 2020
Discovery and characterization of variance QTLs in human induced pluripotent stem cells.PLOS Genetics, 2019
Multi-tissue polygenic models for transcriptome-wide association studies.biorXiv, 2017 (in revision) *Equal contribution
Integrative analysis of 111 reference human epigenomes.Nature, 2015.